Does vitamin D deficiency cause heart disease?

Vitamin D is an important prohormone for optimal substitutional calcium absorption for the mineralization of bone. The vitamin D chemoreceptor is present in multiple tissues, there has been interesting in evaluating other prospective functions of vitamin D, particularly, in cardiovascular diseases. Generality studies have reported that vitamin D deficiency is connected with an increased risk of cardiovascular disease, including hypertension, heart failure, and lifelessness heart disease. Initial prospective studies have also exhibited that vitamin D deficiency increases the risk of developing incident hypertension or sudden cardiac death in individuals with previous cardiovascular disease.

 Expected clinical studies have been conducted to examine the effect of vitamin D supplementation on cardiovascular outcomes. The mechanism for how vitamin D may improve cardiovascular disease, outcomes remains uncertain; however, potential assumptions include the down regulation of the renin-angiotensin-aldosterone system, direct effects on the heart, and vasculature or improvement of glycaemia control. This review would examine the epidemiologic and clinical confirmation for vitamin D deficiency as a cardiovascular risk factor and explore potential mechanisms for the cardio protective effect of vitamin D.

Contemporary studies revealed that vitamin D deficiency results in structural and ionic channel modernization and involuntary maladaptive that may predispose the individuals to lethal cardiac arrhythmias and sudden cardiac death. The expand number of studies point to vitamin D deficiency as a risk influence for heart attacks, congestive heart failure, peripheral arterial disease, strokes, and the conditions related to cardiovascular diseases, and high blood pressure and diabetes.